The nausea and vomiting from cancer treatment is horrendous.  Marijuana contains hundreds of compounds including the psychoactive THC and Nabilone.  Nabilone can help with the nausea and vomiting associated with chemotherapy.  Please consult with a health care provider and local laws prior to seeking marijuana related substances.

The Research

Cancer Chemother Pharmacol. 2017 Mar;79(3):467-477.

doi: 10.1007/s00280-017-3257-1. Epub 2017 Feb 24.

Concise review of the management of iatrogenic emesis using cannabinoids: emphasis on nabilone for chemotherapy-induced nausea and vomiting.

Pergolizzi JV Jr¹, Taylor R¹, LeQuang JA², Zampogna G¹, Raffa RB³.

Author information

Abstract

Chemotherapy-induced nausea and vomiting (CINV) is a prevalent, distressing, and burdensome side effect of cancerchemotherapy. It is estimated to affect the majority of patients receiving certain anti-cancer drug regimens and can be treatment-limiting, even for life-saving medications. Despite seemingly numerous options, such as antimuscarinic anticholinergics, antihistamines, 5-HT₃ receptor antagonists, dopamine receptor antagonists, and neurokinin-1 receptor antagonists, preventative therapies are often inadequately effective, particularly for “delayed CINV”-leaving an important unmet clinical need. Cannabinoid receptor agonists, by virtue of their unique mechanism of action and efficacy and safety data reported in clinical trials, appear to offer a useful additional option. The mechanistic value of cannabinoids has been well known for many years, but these agents may have been underutilized in the past because of the notoriety and legal status of marijuana. While botanical marijuana contains nearly 500 components, including the psychoactive tetrahydrocannabinol (THC), nabilone is an established, single-entity synthetic cannabinoid receptor agonist that has become the focus of renewed interest. We review the basic pharmacology and clinical trial data of nabilone for use in prophylaxis and treatment of CINV.