Can green tea protect your brain in Alzheimer’s?
This study compared the effects of green, black, and red tea on memory function and oxidative stress. Green tea was found to be more protective than red tea or black tea in those with Alzheimer’s disease. Green tea helped with oxidative stress and damage in the hippocampus.
The Research
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Food Res Int. 2017 Oct;100(Pt 1):442-448. doi: 10.1016/j.foodres.2017.07.026. Epub 2017 Jul 14.
Green tea supplementation produces better neuroprotective effects than red and black tea in Alzheimer-like rat model.
Schimidt HL1, Garcia A2, Martins A2, Mello-Carpes PB2, Carpes FP3.
1 Applied Neuromechanics Group, Laboratory of Neuromechanics, Universidade Federal do Pampa, Uruguaiana, RS, Brazil.
2 Physiology Research Group, Stress, Memory and Behavior Lab, Universidade Federal do Pampa, Uruguaiana, RS, Brazil.
3 Applied Neuromechanics Group, Laboratory of Neuromechanics, Universidade Federal do Pampa, Uruguaiana, RS, Brazil. Electronic address: carpes@unipampa.edu.br.
Abstract
Green tea from Camellia sinensis plays a neuroprotective role in different neurodegenerative conditions, such as memory deficits in Alzheimer disease (AD). However, whether other teas from Camellia sinensis present similar neuroprotective effect still is not clear. Here we investigate effects of green, red and black tea supplementation on memory and hippocampus oxidative status in a rat model of Alzheimer-like disease (AD-like).
METHOD:
Wistar male rats were supplemented with green, red or black tea during 8weeks before Aβ intra-hippocampal injection (2μL of Aβ-25-35, CA1 region). AD and sham rats were submitted to memory tests. After euthanasia, oxidative status in the bilateral hippocampus was quantified. Green and red teas avoid memory deficits in AD rats, but only green tea also avoids oxidative stress and damage in the hippocampus. Green tea was more effective for neuroprotection than red and black teas from the Camellia sinensis in the AD rat model.
Copyright © 2017 Elsevier Ltd. All rights reserved.
